ISSN 1866-8836
Клеточная терапия и трансплантация

Volume 2, Number 1(5)
05/17/2010
Volume 2, Number 1(5)
Editor-in-Chief
Afanasyev B. V. (St. Petersburg, Russia)
Co-Editors-in-Chief
Wagemaker G. (Rotterdam, Netherlands)
Zander A. R. (Hamburg, Germany)
Deputy Editor
Chukhlovin A. B. (St. Petersburg, Russia)
Fehse B. (Hamburg, Germany)
Novik A. А. (Moscow, Russia)
Managing Editor
Claudia Koltzenburg (Hamburg, Germany)
Editorial Board
Aleynikova O. (Minsk, Belarus)
Alyansky A. (St. Petersburg, Russia)
Anagnostou A. (Boston, USA)
Andreeff M. (Houston, USA)
Bacher U. (Hamburg, Germany)
Baуkov V. (St. Petersburg, Russia)
Baranov V. S. (St. Petersburg, Russia)
Barkhatov I. (St. Petersburg, Russia)
Baum C. (Hannover, Germany)
Bilko N. (Kiev, Ukraine)
Borset M. (Trondheim, Norway)
Buechner Th. (Muenster, Germany)
Bykov V. (St. Petersburg, Russia)
Dini G. (Genoa, Italy)
Drize N. (Moscow, Russia)
Egeland T. (Oslo, Norway)
Elstner E. (Berlin, Germany)
Emanuel V. (St. Petersburg, Russia)
Everaus H. (Tartu, Estonia)
Ferrara J. (Ann Arbor, USA)
Fibbe W. (Leiden, Netherlands)
Galibin O. (St. Petersburg, Russia)
Ganser A. (Hannover, Germany)
Granov D. (St. Petersburg, Russia)
Ivanov R. (Moscow, Russia)
Klimko N. (St. Petersburg, Russia)
Kolb H.-J. (Muenchen, Germany)
Konopleva M. (Houston, USA)
Koza V. (Pilsen, Czech Republic)
Kroeger N. (Hamburg, Germany)
Malikov A. (St. Petersburg, Russia)
Mikhailova N. (St. Petersburg, Russia)
Mentkevich G. (Moscow, Russia)
Nagler A. (Tel Hashomer, Israel)
Nemkov A. (St. Petersburg, Russia)
Neth R. (Hamburg, Germany)
Nevorotin A.J. (St. Petersburg, Russia)
Ostertag W. (Hamburg, Germany)
Palutke M. (Detroit, USA)
Roumiantsev A. G. (Moscow, Russia)
Savchenko V. G. (Moscow, Russia)
Smirnov A. V. (St. Petersburg, Russia)
Stamm C. (Berlin, Germany)
Tetz V. (St. Petersburg, Russia)
To B. (Adelaide, Australia)
Totolian A. A. (St. Petersburg, Russia)
Uss A.L. (Minsk, Belarus)
Vilesov A. (St. Petersburg, Russia)
Westenfelder Ch. (Salt Lake City, USA)
Wisloff F. (Oslo, Norway)
Zubarovskaya L. (St. Petersburg, Russia)
Zvartau E. (St. Petersburg, Russia)
In this Issue

Abstracts of the joint EBMT Pediatric Working Party – 3rd Raisa Gorbacheva Memorial Meeting, St. Petersburg, Russia, 2009


The aim of the European Group for Blood and Marrow Transplantation (EBMT) is to promote and facilitate access to state-of-the-art and cutting-edge knowledge in blood and marrow transplantation. The EBMT Paediatric Diseases Working Party (EBMT PDWP) has grown during the last few years and currently has more than 20 European countries and at least three non-European countries participating in its activities. This international profile feeds the background against which most of the actual debate on stem cell transplantation in children takes place.

The PDWP firmly believes that children can only be treated by specially trained and experienced pediatric hematopoietic stem cell transplantation (HSCT) teams.

The upcoming meeting will explore the major issues impacting on HSCT in children and adolescents. Leading experts will present and exchange innovative science and discuss specific clinical problems with the audience.

The EBMT PDWP is very enthusiastic about the joint meeting – which will give a full picture of the interdisciplinary approach – and thanks the organizers for the possibility to come to the wonderful venue of St. Petersburg.

Christina Peters
EBMT Chair Paediatric Working Party

Abstracts (Symposium groups)

A. Leukemia treatment
B. Leukemia research
C. Hematopoietic stem cell sources
D. Minimal residual disease
E. Graft-versus-Host Disease
F. Lymphoproliferated diseases (Lymphoma, Myeloma)
G. Complications in hematology (infections, haemostasis abnormalities, fertility)
H. Autoimmune diseases and aplastic anemia
J. Myeloproliferative diseases
K. Inherited diseases
L. Hemoglobinopathies
M. Alternative sources of hematopoietic stem cells (haploidentical relative donors, cord blood)
N. Solid tumors
O. Donor registry

Raisa Gorbacheva Memorial Lecture

A. Leukemia treatment

Prognostic value of chimerism in patients after allogeneic hematopoietic stem cell transplantation (allo-HSCT)

Maria V. Pryanishnikova, Alexandra A. Sipol, Irina S. Solomonova, Ildar M. Barkhatov, Elena V. Semenova, Liudmila S. Zubarovskaya, Boris V. Afanasyev

Efficacy of donor lymphocyte infusions following allogenic stem cell transplantation (allo-HSCT)

Olga A. Slesarchuk, Elena V. Babenko, Maria A. Estrina, Ilya V. Kazantsev, Ludmila S. Zubarovskaya, Boris V. Afanasyev

Survival in adults under 66 years with acute lymphocytic leukemia diagnosed in Norway 2000–2007

Jon-Magnus Tangen1, Jorg Axel Bohl2, Yngvar Floisand3, Einar Haukaas4, Inger Anne Naess5, Tove Skjelbakken6

Epigenetic therapy in childhood AML (pilot study)

Alexander V. Popa1, Elena S. Gorohova2, Elena V. Flejshman3, Larisa G. Fechina4, Vladimir V. Lebedev5, Karapet S. Aslanyan6, Evgenia V. Inyushkina2, Svetlana A. Mayakova1, Irina E. Gavrilova1, Olga P. Chlebnikova4, Elmira G. Boichenko7, George L. Mentkevich1

Comparing efficacy and toxicity of conditioning regimen “treosulfan+cyclophosphomide” versus “busulfan+cyclophosphomide” in children with hematological malignancies after allogeneic hematopoietic stem cell transplantation

Natalia V. Stancheva, Elena V. Semenova, Natalia I. Zubarovskaya, Yulia G. Vasilieva, Vladimir V. Vavilоv, Irina A. Mushchitskaya, Ludmila S. Zubarovskaya, Boris V. Afanasyev

Is it necessary to treat patients after syngeneic bone marrow transplantation?

Lidia S. Lubimova, Larisa A. Kuzmina, Elena N. Parovichnikova, Inna V. Alexeeva, Valeriy G. Savchenko

Treatment results of childhood acute lymphoblastic leukemia using the COALL-Saint-Petersburg-92 protocol after a 10-year observation period

Elmira G. Boichenko1, Margarita B. Belogurova2, Gritta Janka3, Margarita S. Livshits1, Eleonora M. Petrova1, Marina B. Ivanovskaya1, Irina A. Garbusova1, Galyna G. Radulesku2, Tatjana D. Victorovich2, Emylia D. Tchavpetsova2, Ludmila I. Shats2 

Consequences of ABO incompatibility in allogeneic hematopoietic stem cell transplantation (allo-HSCT)

Maria A. Estrina, Мurat O. Yagmourov, Dmitriy E. Pevtsov, Еvgenia A. Kochina, Natalia E. Ivanova, Alla A. Golovacheva, Alexander L. Alyanskiy, Ludmila S. Zoubarovskaya, Abdulbasir A. Ganapiev, Boris V. Afanasyev

B. Leukemia research

Comparative analysis of acute myeloid leukemia treatment results in the Sverdlovsk Regional Clinical Hospital №1

Alexander V. Vinogradov, Tatiana S. Konstantinova, Alexander F. Tomilov, Vladimir A. Shalaev, Elena V. Chepuryaeva, Julia V. Sveshnikova, Leonid N. Sharov, Natalia V. Vinogradova

Posttransplantation leukemia relapses: the role of chromosome changes

Nikolay N. Mamaev, Tatyana L. Gindina, Ildar M. Barkhatov, Boris V. Afanasyev

Determination of FLT3-ITD and D835Y mutations as a factor of prognosis in immunophenotypically verified diagnosis of patients with acute myeloid leukemia in Saint Petersburg

Konstantin U. Slobodnyuk, Irina Y. Saburova, Margarita V. Gorchakova, Ekaterina B. Rusanova, Antonina V. Kurtova, Mikhail I. Zaraiski, Yekaterina E. Zueva

Expression of angiotensin-converting enzymes (ACE, CD143) and shaperons (BiPs, calnexin, calreticulin) by leukemic dendritic cells (LDCs) in acute myeloid leukemia (AML) patients

Irina V. Galtseva1, Lev M. Pashin1, Elena N. Parovichnikova1, Sergei M. Danilov2, Andrei B. Sudarikov1, Ivan A. Vorobiev1, Valeriy G. Savchenko1

C. Hematopoietic stem cell sources

Features of a stem cell’s cryopreservation

Alexander B. Smolyaninov, Ksenia V. Korovina, Shirzod F. Adylov, Elena A. Kotelevskaya

Virus markers antibodies detection in umbilical cord blood

Olga V. Supilnikova, Irina I. Maslenikova, Alexander B. Smolyaninov

Effectiveness of hematopoietic progenitor cell separation with the help of the Sepax S100 cell separator

Alexander B. Smolyaninov, Dmitry A. Ivolgin, Shirzod F. Adylov, Elena A. Kotelevskaya

First experience of CD34+ cell selection to high-risk neuroblastoma patients

Yulia A. Yakovleva1,2, Grigory A. Tsaur1,2, Alexander M. Popov1,2,3, Tatyana Yu. Verzhbitskaya1,2, Igor N. Vyatkin1,2, Andrey A. Igumenshev1,2, Natalya G. Maisheva1,2, Anton Yu. Zadoya1,2, Egor V. Shorikov1,2, Leonid I. Savelyev1,2,3, Larisa G. Fechina1,2

Selection of optimal cryopreservation strategy for hematopoietic stem cells

Leonid I. Savelyev1,2,3, Yulia A. Yakovleva1, Grigory A. Tsaur1,2, Tatyana Yu. Verzbitskaya1,2, Alexander M. Popov1,2,3, Andrey A. Igumenshev1,2, Larisa V. Vakhonina1,2, Igor N. Vyatkin1,2, Egor V. Shorikov1,2, Larisa G. Fechina1,2

Importance of CFU-GM number for prediction of hematological reconstitution after low CD34+ cell dose autotransplantation in children

Yanina I. Isaikina, Valery I. Martinevsky, Nina V. Minakovskaya, Yury S. Strongin, Olga V. Aleinikova

Low and high-resolution HLA typing of cord blood samples of register of donors in St. Petersburg

Elena A. Kotelevskaya, Svetlana A. Smirnova, Alexander B. Smolyaninov

D. Minimal residual disease

Algorithm for monitoring minimal residual disease on the basis of patient-associated immunophenotypes

Yekaterina E. Zueva, Margarita V. Gorchakova, Ekaterina B. Rusanova, Konstantin U. Slobodnyuk

Slow fusion gene transcript clearance predicts poor outcome in infants with MLL-rearranged acute lymphoblastic leukemia

Grigory A. Tsaur1,2, Tatyana V. Nasedkina3, Alexander M. Popov1,2,4, Anna S. Ivanova1,2, Yulia A. Yakovleva1,2, Tatyana O. Riger1,2, Egor V. Shorikov1,2, Leonid I. Saveliev1,2,4, Larisa G. Fechina1,2

Comparison of MRD data assessed by flow cytometry and RT-PCR of fusion gene transcripts in infants with MLL-rearranged ALL

Alexander M. Popov1,2,3, Grigory A. Tsaur1,2, Anna S. Ivanova1,2, Yulia A. Yakovleva1,2, Tatiana Y. Verzhbitskaya1,2, Tatiana O. Riger1, Egor V. Shorikov1,2, Leonid I. Savelyev1,2,3, Larisa G. Fechina1,2

Detection of minimal residual disease (MRD) by flow cytometry in children with acute lymphoblastic leukemia (ALL)

Margarita G. Bozhieva, Ludmila Y. Grivtsova, Alexander V. Popa, Irina N. Serebryakova, Irina E. Gavrilova, Boris V. Kurdyukov, Rono S. Ravshanova, Georgiy L. Mentkevich, Nikolay N. Tupitsyn

E. Graft-versus-Host Disease

The comparative characteristic toxicity and immunosuppressive activity both tacrolimus and cyclosporine in patients undergoing allo-HSCT

Yulia A. Stankevich, Ludmila S. Zubarovskaya, Elena V. Semenova, Sergey M. Alexeev, Elena V. Babenko, Boris V. Afanasyev

Evidence of the “graft-versus-tumor” effect following haploidentical transplantation in a patient with a metastatic relapse of Ewing’s sarcoma

Igor S. Dolgopolov, Roman I. Pimenov, Vasilii K. Boyarshinov, Natalia S. Subbotina, George L. Mentkevich

Spirometry findings in bone marrow transplant patients

Larisa A. Kuzmina, Lidia S. Lubimova, Valeriy G. Savchenko

F. Lymphoproliferated diseases (Lymphoma, Myeloma)

Association between HLA class I antigens and survival length in patients with multiple myeloma

Elena A. Senkina, Galina A. Zaitseva, Tamara P. Zagoskina, Konstantin A. Martynov

Bone marrow angiogenesis is a prognostic value in patients with multiple myeloma undergoing high-dose therapy and autologous stem cell transplantation

Olga S. Pokrovskaya, Lidia S. Mendeleeva, Irina B. Kaplanskaya, Elena Yu. Varlamova, Elena N. Parovichnikova, Sergey M. Kulikov, Valeriy G. Savchenko

Allogeneic stem cell transplantation in multiple myeloma: single centre experience of 112 patients

Liisa Volin, Heli Uotinen, Eeva Juvonen, Anne Nihtinen, Tapani Ruutu

Virus participation in renal damage in AL patients: histopathological study

Ekaterina G. Vorozheikina1, Vladimir V. Varshavski2, Ekaterina P. Golitsina2, Evgenia N. Glasko1, Irina B. Kaplanskaya1, Ljudmila S. Birjukova1, Elena N. Parovichnikova1, Valeriy G. Savchenko1

The role of p53 polymorphisms in non–Hodgkin’s lymphomas’ susceptibility and prognosis

Elena N. Voropaeva, Tatiana I. Pospelova, Mikhail I. Voevoda, Olga V. Beresina

High-dose melphalan versus melphalan plus dexamethasone in patients with AL amyloidosis

Anna G. Smirnova1, Alexey V. Smirnov2, Axel R. Zander3, Boris V. Afanasyev1

Prognostic value of apoptosis of tumor clone bone marrow cells in patients with multiple myeloma

Zhanna V. Chubukina, Ludmila N. Bubnova, Stanislav S. Bessmeltsev

Salvage therapy in relapsed Hodgkin's lymphoma patients

Elena S. Belyaeva, Olga V. Morozova, Andrey I. Slugin, Alexander V. Popa, Georgy L. Mentkevich

Impact of positron emission tomography on primary staging and changing the therapeutic modality in lymphoma patients

Natalia B. Mikhaylova1, Marina S. Tlostanova2, Yulia N. Vinogradova2, Ekaterina I. Ivanova2, Anna V. Kritskaya2, Sergey E. Korolev1, Anna A. Rats1, Alexander A. Pugachev1, Nikolay V. Ilyin2, Boris V. Afanasyev1, Leonid A. Tyutin2

Expression of tumor-associated genes in multiple myeloma patients during high-dose chemotherapy and auto-SCT

Tatiana V. Gaponova, Lidia S. Mendeleeva, Andrey V. Misurin, Elena Yu. Varlamova, Elena N. Parovichnikova,
Valeriy G. Savchenko

Treatment results of children with Hodgkin’s disease (HD) according to protocols DAL-HD and GPOH-HD

Margarita B. Belogurova1,2, Galina G. Radulesku1,2, Tatyana D. Viktorovich1,2, Emilia D. Chavpetsova2, Ludmila I. Shats1,2, Yulia V. Dinikina1

Cellular factors of antitumor immunity in patients with chronic lympholeukemia

Natalya V. Issayeva, Galina A. Zaitseva, Tamara P. Zagoskina

Anemias in lymphomas: pathogenesis mechanisms

Anna S. Lyamkina, Tatiana I. Pospelova

Clinical and pathological characterization of the t(14;19)(q32;q13)-positive splenic marginal zone lymphoma

Hunan L. Julhakyan, Tatyana N. Obukhova, Irina B. Kaplanskaya, Rima S. Samoylova, Andrey I. Vorobiev

G. Complications in hematology (infections, haemostasis abnormalities, fertility)

C-reactive protein (CRP) concentration in patients with acute myeloblastic leukemia (AML) manifestation

Sofia G. Vladimirova, Lyudmila N. Tarassova, Gulzada N. Mustafina, Valentina V. Cherepanova

Invasive fungal disease (IFD) in patients after allogeneic hematopoietic stem cell transplantation: single center experience

Natalia I. Zubarovskaya1, Yulia G. Vasilieva1, Natalia V. Stancheva1, Elena V. Semenova1, Vladimir N. Vavilov1, Svetlana Emelyanova2, Nikolay N. Klimko3, Boris V. Afanasyev1

Epidemiology of bacterial infections and antibiotic resistance in BMT clinic: single center experience

Vladimir N. Vavilov1, Olga B. Ponomarenko1, Marina O. Popova1, Svetlana S. Emelyanova2, Maria Yu. Averjanova1, Oleg V. Goloschapov1, Ludmila S. Zubarovskaya1, Boris V. Afanasyev1

Correlations between reactivation of herpesviruses and common complications of allo-HSCT

Olga S. Pankratova, Alexey B. Chukhlovin, Ludmila S. Zubarovskaya, Boris V. Afanasyev

Management of resistant or recurrent CMV infection following allogeneic SCT

Petr Sedlacek1, Ladislav Krol1, Petr Hubacek1, David Boutolleau2, Tomas Kalina1

Hemostasis in patients with acute myeloblastic leukemia (AML) manifestation

Valentina V. Cherepanova, Sofia G. Vladimirova, Lyudmila N. Tarassova, Gulzada N. Mustafina, Natalia N. Silina

H. Autoimmune diseases and aplastic anemia

Outcomes of hematopoietic cell transplantation (SCT) and combined immunosupression (IST) patients with severe aplastic anemia (SAA) admitted with life-threatening infections

Galina A. Novichkova, Mikhail A. Maschan, Lili A. Khachatrian, Dina D. Baidildina, Olga V. Goronkova, Galina G. Solopova, Elena V. Skorobogatova, Irina P. Shipitsina, Alexey A. Maschan

Alternative method for treating acquired aplastic anemia

Yuri I. Yugov, Nina A. Fedorovskaya, Alexander S. Luchinin

Mesenchymal stem cell transplantation in patents with amyotrophic lateral sclerosis and multiple sclerosis

Miroslav M. Odinak1, Gennadiy N. Bisaga1, Andrey V. Novitsky2, Vadim V. Tirenko2, Dmitriy N. Sculyabin1, Dmitriy G. Polyntsev3, Petr V. Krugliakov3, Anna N. Bilibina3, A. Kolchenko3

Immunoablation followed by autologous stem cell transplantation in refractory autoimmune diseases: clinical outcomes and immune reconstitution

Igor A. Lisukov1,2, Vera V. Sergeevicheva2, Svetlana A. Sizikova2, Alexander D. Kulagin1,2, Irina V. Kruchkova2, Andrey V. Gilevich2, Alexey E. Sizikov2, Lyudmila P. Konenkova2, Elena R. Chernykh2, Vladimir S. Kozhevnikov2, Alexander A. Demin1, Vladimir A. Kozlov2

The severity of acquired aplastic anemia (AA) and long-term prognosis: lessons from current results of immunosuppressive treatment (IST)

Alexander D. Kulagin1,2, Igor A. Lisukov1,2, Vyacheslav I. Borisov2, Irina V. Kruchkova2, Vera V. Sergeevicheva2, Svetlana A. Sizikova2, Andrey V. Gilevich2, Vladimir S. Kozhevnikov2, Vladimir A. Kozlov2

J. Myeloproliferative diseases

Index granularity of neutrophils in peripheral blood as a new application for screening myelodysplastic syndromes using flow cytometry

Ekaterina B. Rusanova1, Konstantin U. Slobodnyuk1, Margarita V.Gorchakova1, Yekaterina E. Zueva1, Ramon Simon-Lopez2

Case report: combined myeloid and lymphoid lineage disorders in patient with chronic eosinophilic leukemia and T-cell lymphoma

Margarita V. Gorchakova, Ekaterina B. Rusanova, Konstantin U. Slobodnyuk, Irina J. Saburova, Elena A. Stadnik, Michail I. Zaraiski, Yekaterina E. Zueva

K. Inherited diseases

Hematopoietic stem cell transplantation (HSCT) in patients with severe combined immunodeficiency (SCID): experiences, possibilities, and prospects

Dmitry N. Balashov, Pavel E. Trakhtman, Elena V. Skorobogatova, Yulia V. Skvortsova, Zarema M. Dyshlevaja, Irina P. Shipitsina, Alexey A. Maschan, Alexander G. Rumyantsev

L. Hemoglobinopathies

Outcomes after addition of rabbit-ATG to the standard Bu+CY preparative regimen for allogeneic matched sibling donor (MSD) hematopoietic stem cell transplantation (HSCT) for hemoglobinopathies in children: a single center experience

Sandeep Soni, MD1, Micah Skeens, RN, MSN1, Thomas E. Gross, MD1, Rajinder P. Bajwa, MD1, Kathryn Klopfenstein, MD2,
K. Scott Baker, MD, MS3, Amanda M.Termuhlen, MD1

M. Alternative sources of hematopoietic stem cells (haploidentical relative donors, cord blood)

Haploidentical SCT as a salvage therapy in hematological malignancies: A single center experience

Olesya V. Paina, Yulia A. Stankevich, Ilya V. Kazantsev, Natalia V. Stancheva, Alla A. Golovacheva, Elena V. Babenko, Alexander L. Alyanskiy, Natalia E. Ivanova, Elena V. Semenova, Petr V. Krugliakov, Dmitriy G. Polyntsev, Liudmila S. Zubarovskaya, Boris V. Afanasyev

Non-T-cell depleted haploidentical HSCT after RIC in pediatric malignancies

Natalia S. Subbotina, Igor S. Dolgopolov, Roman I. Pimenov, Vasilii K. Boyarshinov, George L. Mentkevich

Properties of cord blood stem cells chromatin

Vladimir S. Tolmachev, Elizaveta I. Borovitskaya, Natalia O. Kudrina, Tatiana G. Kravtsova

Prognostic factors in cord blood stem cell quality

Artur A. Isaev, Alexander V. Prihodko, Sergey L. Kiselev, Maria A. Lagarkova, Ivan V. Potapov, Alexey V. Lundup

Developing new immunological compatible transplants derived from umbilical cord

Artur A. Isaev1, Alexander V. Prihodko1, Irina N. Saburina2, Sergey L. Kiselev1, Varvara S. Melihova2, Ivan V. Potapov1, Alexey V. Lundup1

N. Solid tumors

Aggressiveness of tumor resection improves survival in pediatric malignant gliomas

Ludmila I. Shats1, Margarita B. Belogurova1, Olga G. Zheludkova 2

First experience of treatment of high-risk neuroblastoma patients using autologous peripheral blood stem cells transplantation

Igor N. Vyatkin1,2,  Egor V. Shorikov1,2, Andrey A. Igumenshev1,2, Larisa V. Vakhonina1,2, Natalya G. Maisheva1,2, Yulia A. Yakovleva1,2, Grigory A. Tsaur1,2, Alexander M. Popov1,2,3, Elizaveta R. Semenikhina1, Leonid I. Savelyev1,2,3, Larisa G. Fechina1,2

Treatment of patients with high-risk axial and pelvic Ewing’s sarcoma (ES). A single-institution experience

Roman I. Pimenov1, Igor S. Dolgopolov1, Vasilii K. Boyarshinov1, Natalia S. Subbotina1, Igor V. Visochin1, Stuart Siegiel2, George L. Mentkevich1

Restoration of ovarian function after cryopreserved ovarian tissue transplantation in women exposed to complex treatment for gynecological cancer: feasibility of this option in pediatric cancer patients

Alla S. Lisyanskya1,2, Natalia I. Tapilskaya1,3, Margarita B. Belogurova3,4, Yulia V. Dinikina3, Ekaterina V. Tsibatova4, Georgy M. Manikhas1

High-dose chemotherapy and autologous stem cell transplantation in children with Ewing’s sarcoma/PNET

Ilya V. Kazantsev1, Tatjana V. Youhta2, Elena V. Morozova1, Svetlana A. Safonova2, Yury A. Punanov2, Liudmila S. Zubarovskaya1, Boris V. Afanasyev1

The outcome of treatment in patients with high-risk (HR) retinoblastoma

Igor S. Dolgopolov1, Tatiana L. Ushakova1, Olga N. Gorovtzova1, Alevtina I. Pavlovskaya2, Roman I. Pimenov1, Vasilii K. Boyarshinov1, Natalia S. Subbotina1, Igor V. Glekov1, Vladimir G. Poliakov1, George L. Mentkevich1

O. Donor registry

Influence of differentiated occurrence of HLA genes and haplotypes on defined clinical parameters in patients after allo–HSCT in association with HLA polymorphism

Alexander L. Alyanskiy, Olesya V. Paina, Natalia E. Ivanova, Alla A. Golovacheva, Ludmila S. Zubarovskaya, Boris V. Afanasyev