ISSN 1866-8836
Клеточная терапия и трансплантация

Cellular Therapy and Transplantation is an international, peer-reviewed, Open Access journal which publishes articles in the fields of cellular and gene therapy and tissue transplantation. We welcome original research articles, review articles, short communications and clinical case reports. The major criteria for acceptance and publication of a manuscript are originality, high quality, scientific rigor, and interest to a wide audience of readers. The journal is issued in printed and digital version (

Editorial work, processing and publication of the articles are free of charge for the authors.

Papers accepted for publication in CTT are made available on this site at no charge to readers (Open Access). The articles published in CTT are provided under the following license: Creative Commons Attribution 3.0 Unported, Authors retain the copyright of their contributions.
Volume 8, number 1
Volume 8, number 1
Afanasyev B. V. (St. Petersburg, Russia)
Wagemaker G. (Rotterdam, Netherlands)
Zander A. R. (Hamburg, Germany)
Deputy Editor
Fehse B. (Hamburg, Germany)
Managing Editor
Chukhlovin A. B. (St. Petersburg, Russia)
Editorial Board
Aleynikova O. V. (Minsk, Belarus)
Borset M. (Trondheim, Norway)
Chechetkin A. V. (St. Petersburg, Russia)
Fibbe W. (Leiden, Netherlands)
Galibin O. V. (St. Petersburg, Russia)
Hölzer D. (Frankfurt a.M., Germany)
Klimko N. N. (St. Petersburg, Russia)
Kolb H.-J. (München, Germany)
Kröger N. (Hamburg, Germany)
Kulagin A. D. (St. Petersburg, Russia)
Lange C. (Hamburg, Germany)
Mamaev N. N. (St. Petersburg, Russia)
Mikhailova N. B. (St. Petersburg, Russia)
Moiseev I. S. (St. Petersburg, Russia)
Nagler A. (Tel-Aviv, Israel)
Nemkov A. S. (St. Petersburg, Russia)
Paramonov I. V. (Kirov, Russia)
Roumiantsev A. G. (Moscow, Russia)
Savchenko V. G. (Moscow, Russia)
Smirnov A. V. (St. Petersburg, Russia)
Uss A. L. (Minsk, Belarus)
Zubarovskaya L. S. (St. Petersburg, Russia)
In this Issue
Short review by Prof. Tapani Ruutu opens the issue. It is dedicated to thrombotic angiopathy, a common complication of conditioning therapy in hematopoietic stem cell transplantation (HSCT). Special attention is drawn to erythrocyte schistocytosis as a marker of capillary damage, and its correct diagnostics.

Another review paper by O. V. Galibin et al. concerns natural and synthetic matrices developed for faster and effective regeneration of damaged nerves. Special attention is given to chitosan-containing polymers and biodegradable, electroconductive synthetic carriers allowing to perform regeneration-promoting procedures.

An article by A. B. Chukhlovin deals with some “old” drugs used in a number of non-oncological disorders which may be, in addition, applied for cancer therapy, mostly as a components of combined therapy.

Clinical results of hematopoietic stem cell transplantation from haploidentical donor (e.g., the patients’ parents) are presented in the paper by A. V. Beynarovich et al., addressing mostly clinical outcomes (early and late survival, relapse rates etc. based on a single-center experience.

Prognostic scales in the patients with myelodysplastic syndrome (MDS) show different efficiency, especially when treated with novel therapies. E.V.Morozova et al. compare different prognostic scales in MDS, with respect to appropriate clinical outcomes at long observation terms.

A specialized diagnostics and medical assistance are required in HSCT patients with ORL complications in HSCT patients. These issues are described by E. S. Utimisheva et al. who have focused on sinusitis, its bacterial pathogens, therapeutic effects of maxillary punctures in the patients.

Special clinical case is described by T. A. Bykova et al. who present a description of a patient with a case of familial hemophagocytic lymphohistiocytosis, a rare clinical entity which shows genetic predisposition in some instances.

An experimental study by A. V. Kuznetsov et al. provides original data about mitotic activity and contents of cell in thoracic duct lymph of rabbits, starting from newborns to young adults. Evidence for dividing cells makes it possible to apply these results to the issues of immune recovery in very young mammals including humans, thus being of potential importance in cytostatic therapy.

Editorial article

Editorial article

Professor Boris V. Afanasyev, Editor-in-Chief, Cellular Therapy and Transplantation Journal

Review articles

Alternative approaches to overcome diastasis of damaged peripheral nerves. A review article

Oleg V. Galibin1, German V. Medvedev2, Pavel V. Popryadukhin3, Pavel A. Kulagin1, Alexandr A. Gusev1, Galina P. Kossyakova1, Natalia V. Mikhailova1, Veronika D. Novak1, Denis N. Solomitskiy1, Igor O. Shemiakin1, Vadim S. Gadzhiagaev1, Maksat Kh. Gurbannazarov1

Clinical studies

Application of standard and novel prognostic systems in patients with myelodys- plastic syndrome undergoing allogeneic hematopoietic stem cell transplantation

Elena V. Morozova, Maria V. Barabanshikova, Nikolai Yu. Tcvetkov, Ksenia V. Melsitova, Julia V. Rudnitskaya, Elena I. Darskaya, Sergey N. Bondarenko, Ivan S. Moiseev, Boris V. Afanasyev

Haploidentical stem cell transplantation in adults for the treatment of hematologic diseases: results of a single center (CIC725)

Anastasia V. Beynarovich, Elena V. Babenko, Ivan S. Moiseev, Olesya V. Paina, Olga V. Pirogova, Tatiana A. Rudakova, Tatyana L. Gindina, Elena I. Darskaya, Elena V. Morozova, Sergey N. Bondarenko, Ludmila S. Zubarovskaya, Boris V. Afanasyev

Incidence, diagnosis and treatment of sinusitis in children and adolescents after hematopoietic stem cell transplantation

Ekaterina S. Utimisheva1, Oleg I. Dolgov1, Olesya V. Paina1, Kirill A. Ekushov1, Alina A. Vitrischak1, Boris I. Smirnov2, Ludmila S. Zubarovskaya1, Sergey A. Karpischenko1, Boris V. Afanasyev1

Clinical case

A clinical case of familial hemophagocytic lymphohistiocytosis

Tatiana A. Bykova, Varvara N. Ovechkina, Anna A. Osipova, Andrey V. Kozlov, Alexander L. Alyanskiy, Elena V. Semenova, Ludmila S. Zubarovskaya, Boris V. Afanasyev

Experimental studies

Mitotic activity of thoracic duct cells in rabbits correlates with age and total lymphocyte numbers

Alexander V. Kuznetsov1, Ildar R. Fakhradiyev2, Ydyrys A. Almabayev3, Aigul Y. Almabayeva4