ISSN 1866-8836
Клеточная терапия и трансплантация

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Editorial

Pavlov University: 125 years in blood research

Professor Alexander D. Kulagin, Editor-in-Chief, Cellular Therapy and Transplantation Journal

Editorial

Pavlov University: 125 years in blood research

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Professor Alexander D. Kulagin, Editor-in-Chief, Cellular Therapy and Transplantation Journal

In 2022, the First St. Petersburg State Medical University (Pavlov University) is celebrating its 125th anniversary. The studies in clinical hematology and immunology developed here since early XX century at the Chair of Faculty Therapy. Its future head, Prof. Georg F. Lang later became a famous cardiologist. However, his Doctor’s Thesis (1901) was dedicated to osmotic resistance of red blood cells in stomach cancer and other malignancies. He presented original experimental studies on regulation of red blood cells and hemolysis. Later on, professor T. S. Istamanova headed the chair, being the best successor of his school. She was among founders of functional hematology, proceeded with studies in physiology and pathology of erythropoiesis performed since 20s. Her experimental works concerned the role of spleen in red blood cell destruction, neurogenic regulation of hematopoiesis, functional significance of reticulocytosis in hematopoietic function. Prof. T. S. Istamanova was deeply involved into clinical aspects of polycythemia. Functional dynamics of erythroid cells was extensively studied over 40s and 50s, especially, using innovative assays of hemoglobin metabolism with 59Fe and other radionuclides.